Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 2B
Ligand
BDBM50014407
Substrate
n/a
Ki
460±n/a nM
Comments
PDSP_1578
Citation
 McKenna, DJ; Peroutka, SJ Differentiation of 5-hydroxytryptamine2 receptor subtypes using 125I-R-(-)2,5-dimethoxy-4-iodo-phenylisopropylamine and 3H-ketanserin. J Neurosci 9:3482-90 (1989) [PubMed] 
Target
Name:
5-hydroxytryptamine receptor 2B
Synonyms:
5-HT2B | 5-hydroxytryptamine 2B receptor | HTR2B
Type:
Enzyme Catalytic Domain
Mol. Mass.:
15564.62
Organism:
BOVINE
Description:
Q8MI09
Residue:
137
Sequence:
KPPQRLTWLTVSTVFQRDETPCSSPEKVAMLDGFHKDKTLPNASADILMRRMSTVGKKSVQTISNEQRASKVLGIVFFLFLLMWCPFFITNVTLVLCDSCNQTTLNMLLEIFVWIGYVSSGVNPLVYTLFNKTFRDA
  
Inhibitor
Name:
BDBM50014407
Synonyms:
2-(piperazin-1-yl)quinoline | 2-Piperazin-1-yl-quinoline | 2-Piperazin-1-yl-quinoline (Quipazine) | 2-Piperazin-1-yl-quinoline(Quipazine) | CHEMBL18772 | QUIPAZINE
Type:
Small organic molecule
Emp. Form.:
C13H15N3
Mol. Mass.:
213.2783
SMILES:
C1CN(CCN1)c1ccc2ccccc2n1
Structure:
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