Reaction Details Report a problem with these data
Target
Cholecystokinin
Ligand
BDBM50008673
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_2243
Citation
 Evans, BE; Bock, MG; Rittle, KE; DiPardo, RM; Whitter, WL; Veber, DF; Anderson, PS; Freidinger, RM Design of potent, orally effective, nonpeptidal antagonists of the peptide hormone cholecystokinin. Proc Natl Acad Sci U S A 83:4918-22 (1986) [PubMed]  Article 
Target
Name:
Cholecystokinin
Synonyms:
CCKN_RAT | Cck
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12844.29
Organism:
RAT
Description:
Cholecystokinin 0 RAT::P01355
Residue:
115
Sequence:
MKCGVCLCVVMAVLAAGALAQPVVPVEAVDPMEQRAEEAPRRQLRAVLRPDSEPRARLGALLARYIQQVRKAPSGRMSVLKNLQGLDPSHRISDRDYMGWMDFGRRSAEDYEYPS
  
Inhibitor
Name:
BDBM50008673
Synonyms:
2-(4-Chloro-benzoylamino)-3-(1H-indol-3-yl)-propionic acid | 2-(4-Chloro-benzoylamino)-3-(1H-indol-3-yl)-propionic acid (benzotript) | Benzotript | CHEMBL96074
Type:
Small organic molecule
Emp. Form.:
C18H15ClN2O3
Mol. Mass.:
342.776
SMILES:
OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c1ccc(Cl)cc1
Structure:
Search PDB for entries with ligand similarity: