Reaction Details
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Report a problem with these dataTarget
Melatonin receptor type 1A
Ligand
BDBM50043289
Substrate
n/a
Ki
0.25±n/a nM
Comments
PDSP_1195
Citation
Reppert, SM; Weaver, DR; Ebisawa, T Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses. Neuron 13:1177-85 (1994) [PubMed] Article More Info.:
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTR1A_SHEEP | Melatonin | Melatonin receptor type 1A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40421.02
Organism:
Sheep
Description:
Melatonin 0 Sheep::P48040
Residue:
366
Sequence:
MAGRLWGSPGGTPKGNGSSALLNVSQAAPGAGDGVRPRPSWLAATLASILIFTIVVDIVGNLLVVLSVYRNKKLRNAGNVFVVSLAVADLLVAVYPYPLALASIVNNGWSLSSLHCQLSGFLMGLSVIGSVFSITGIAINRYCCICHSLRYGKLYSGTNSLCYVFLIWTLTLVAIVPNLCVGTLQYDPRIYSCTFTQSVSSAYTIAVVVFHFIVPMLVVVFCYLRIWALVLQVRWKVKPDNKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLVVASDPASMAPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRQEYRKIIVSLCTTKMFFVDSSNHVADRIKRKPSPLIANHNLIKVDSV
Inhibitor
Name:
BDBM50043289
Synonyms:
CHEMBL34730 | N-[2-(6-Chloro-5-methoxy-1H-indol-3-yl)-ethyl]-acetamide | N-[2-(6-Chloro-5-methoxy-1H-indol-3-yl)-ethyl]-acetamide(6-Chloromelatonin) | melatonin, 6-Chloro
Type:
Small organic molecule
Emp. Form.:
C13H15ClN2O2
Mol. Mass.:
266.723
SMILES:
COc1cc2c(CCNC(C)=O)c[nH]c2cc1Cl
Structure:
