Reaction Details Report a problem with these data
Target
D(4) dopamine receptor
Ligand
BDBM85067
Substrate
n/a
Meas. Tech.
ChEMBL_1688620 (CHEMBL4039190)
Ki
3±n/a nM
Citation
 Lindsley, CW; Hopkins, CR Return of D J Med Chem 60:7233-7243 (2017) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Human
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM85067
Synonyms:
CAS_170856-41-4 | CHEMBL81330 | PNU 96415E | PNU-96415E
Type:
Small organic molecule
Emp. Form.:
C21H25FN2O
Mol. Mass.:
340.4344
SMILES:
Fc1ccc(cc1)N1CCN(CCC2OCCc3ccccc23)CC1
Structure:
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