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Target
Platelet-activating factor receptor
Ligand
BDBM50013923
Substrate
n/a
Meas. Tech.
ChEBML_154992
IC50
1±n/a nM
Citation
 Guthrie, RW; Kaplan, GL; Mennona, FA; Tilley, JW; Kierstead, RW; O'Donnell, M; Crowley, H; Yaremko, B; Welton, AF Propenyl carboxamide derivatives as antagonists of platelet activating factor. J Med Chem 33:2856-64 (1990) [PubMed]  Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF Platelet activating factor | PAF-R | PAFR | PTAFR | PTAFR_HUMAN | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39219.60
Organism:
Homo sapiens (Human)
Description:
PAF Platelet activating factor PTAFR HUMAN::P25105
Residue:
342
Sequence:
MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLTMADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVTRPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKGSVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAVFIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
  
Inhibitor
Name:
BDBM50013923
Synonyms:
3-(1-Butyl-4-methoxy-naphthalen-2-yl)-N-(1-methyl-4-pyridin-3-yl-butyl)-acrylamide | CHEMBL99294
Type:
Small organic molecule
Emp. Form.:
C28H34N2O2
Mol. Mass.:
430.5818
SMILES:
CCCCc1c(\C=C\C(=O)N[C@@H](C)CCCc2cccnc2)cc(OC)c2ccccc12
Structure:
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