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Target
D(2) dopamine receptor
Ligand
BDBM50017464
Substrate
n/a
Meas. Tech.
ChEMBL_59486 (CHEMBL670138)
Ki
6±n/a nM
Citation
 Craig, JC; Torkelson, SM; Findell, PR; Weiner, RI Synthesis and dopaminergic activity of 2-substituted octahydrobenzo[f]quinolines. J Med Chem 32:961-8 (1989) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DRD2 | DRD2_BOVIN | Dopamine D2 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50698.79
Organism:
BOVINE
Description:
P20288
Residue:
444
Sequence:
MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50017464
Synonyms:
(8,9-Dihydroxy-4-propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-2-yl)-acetonitrile | CHEMBL173250
Type:
Small organic molecule
Emp. Form.:
C18H24N2O2
Mol. Mass.:
300.3954
SMILES:
CCCN1C[C@H](CC#N)C[C@H]2[C@H]1CCc1cc(O)c(O)cc21
Structure:
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