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Target
Gamma-hydroxybutyrate receptor
Ligand
BDBM50023573
Substrate
n/a
Meas. Tech.
ChEBML_68885
IC50
3.3±n/a nM
Citation
 Bourguignon, JJ; Schoenfelder, A; Schmitt, M; Wermuth, CG; Hechler, V; Charlier, B; Maitre, M Analogues of gamma-hydroxybutyric acid. Synthesis and binding studies. J Med Chem 31:893-7 (1988) [PubMed]  Article 
Target
Name:
Gamma-hydroxybutyrate receptor
Synonyms:
Gamma hydroxybutyric, GHB | Gamma-hydroxybutyrate receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
56171.11
Organism:
RAT
Description:
Gamma hydroxybutyric, GHB 0 RAT::Q6RY99
Residue:
512
Sequence:
MRAAAAGLGPGRLHAWAARRGLGRFPARVPRAAGGRSPCPASISNSRTLRLAAAGNTFCLASTLSSGCWEPCSWPSASGPGVRRAFFPTSQGGQIQGGLDPVWLFVVIGGIMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELAAGILAFVFKDWIRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIRTSTALTSNPSRERCGVPFFCWVRTLRKTSQYPCGYTSAQTELEHKIHLHQSWWPFEKWLKKPDGWPGLGAIASFKMGIAGPNPRSTSRQERPTGKLPGVMATCLAHRAVVGASKDALPHSQWQGLWDVCYDLSPRLCEHGTQEATEAGLGLNWGCTGAGLGLFTTELCVWGVHMCVCVCVCVCVRVCLCLCVRVRGMHVCALVSTPGVSTPLLVRWWPFQSFKGDGARRVGHVPASPSLLWDVSLCGLGACCLRPLHIHHDLEPAWSSPWPQCHSLEMGPRILSVSLSRLPLRTHTWQDGYERLN
  
Inhibitor
Name:
BDBM50023573
Synonyms:
4-Cyclohexyl-4-hydroxy-but-2-enoic acid | CHEMBL171331
Type:
Small organic molecule
Emp. Form.:
C10H16O3
Mol. Mass.:
184.2322
SMILES:
OC(\C=C\C(O)=O)C1CCCCC1
Structure:
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