Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50464599
Substrate
n/a
Meas. Tech.
ChEMBL_1781840 (CHEMBL4253357)
Ki
642±n/a nM
Citation
 Galal Osman, A; Elokely, KM; Yadav, VK; Carvalho, P; Radwan, M; Slade, D; Gul, W; Khan, S; Dale, OR; Husni, AS; Klein, ML; Cutler, SJ; Ross, SA; ElSohly, MA Bioactive products from singlet oxygen photooxygenation of cannabinoids. Eur J Med Chem 143:983-996 (2018) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50464599
Synonyms:
CHEMBL4292923
Type:
Small organic molecule
Emp. Form.:
C28H36O5S
Mol. Mass.:
484.647
SMILES:
[H][C@@]12CC=C(C)[C@@H](O)[C@@]1([H])c1c(OS(=O)(=O)c3ccc(C)cc3)cc(CCCCC)cc1OC2(C)C |r,t:3|
Structure:
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