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Target
Matrix protein 2
Ligand
BDBM50465105
Substrate
n/a
Meas. Tech.
ChEMBL_1784189 (CHEMBL4255706)
Kd
320±n/a nM
Citation
 Drakopoulos, A; Tzitzoglaki, C; McGuire, K; Hoffmann, A; Konstantinidi, A; Kolokouris, D; Ma, C; Freudenberger, K; Hutterer, J; Gauglitz, G; Wang, J; Schmidtke, M; Busath, DD; Kolocouris, A Unraveling the Binding, Proton Blockage, and Inhibition of Influenza M2 WT and S31N by Rimantadine Variants. ACS Med Chem Lett 9:198-203 (2018) [PubMed]  Article 
Target
Name:
Matrix protein 2
Synonyms:
M | M2_I72A8 | Proton channel protein M2
Type:
PROTEIN
Mol. Mass.:
11180.06
Organism:
Influenza A virus (A/Udorn/307/1972(H3N2))
Description:
ChEMBL_22
Residue:
97
Sequence:
MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFEHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIELE
  
Inhibitor
Name:
BDBM50465105
Synonyms:
CHEMBL1235691
Type:
Small organic molecule
Emp. Form.:
C12H21N
Mol. Mass.:
179.3018
SMILES:
[H][C@](C)(N)C12CC3([H])CC([H])(CC([H])(C3)C1)C2 |r,TLB:8:9:15:5.6.14,THB:8:6:15:16.9.11,11:9:5:15.12.14,11:12:5:16.9.8|
Structure:
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