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Target
D(1A) dopamine receptor
Ligand
BDBM50473127
Substrate
n/a
Meas. Tech.
ChEMBL_58816 (CHEMBL668240)
Ki
389±n/a nM
Citation
 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Binding and preliminary evaluation of 5-hydroxy- and 10-hydroxy-2,3, 12,12a-tetrahydro-1H-[1]benzoxepino[2,3,4-ij]isoquinolines as dopamine receptor ligands. J Med Chem 43:599-608 (2000) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49429.75
Organism:
Rat
Description:
P18901
Residue:
446
Sequence:
MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
  
Inhibitor
Name:
BDBM50473127
Synonyms:
CHEMBL154301
Type:
Small organic molecule
Emp. Form.:
C18H19Br2NO2
Mol. Mass.:
441.157
SMILES:
COc1ccc(Br)c(CC2N(C)CCc3c(Br)ccc(O)c23)c1
Structure:
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