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Target
D(2) dopamine receptor
Ligand
BDBM50474703
Substrate
n/a
Meas. Tech.
ChEMBL_60398 (CHEMBL672843)
Ki
<6.00±n/a nM
Citation
 Lyles-Eggleston, M; Altundas, R; Xia, J; Sikazwe, DM; Fan, P; Yang, Q; Li, S; Zhang, W; Zhu, X; Schmidt, AW; Vanase-Frawley, M; Shrihkande, A; Villalobos, A; Borne, RF; Ablordeppey, SY Design, synthesis, and evaluation of metabolism-based analogues of haloperidol incapable of forming MPP+-like species. J Med Chem 47:497-508 (2004) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Human
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50474703
Synonyms:
CHEMBL1269
Type:
Small organic molecule
Emp. Form.:
C21H18ClFNO
Mol. Mass.:
354.825
SMILES:
Fc1ccc(cc1)C(=O)CCC[n+]1ccc(cc1)-c1ccc(Cl)cc1
Structure:
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