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Target
RNA-directed RNA polymerase
Ligand
BDBM50537570
Substrate
n/a
Meas. Tech.
ChEMBL_1969961 (CHEMBL4602779)
IC50
45000±n/a nM
Citation
 Ganta, NM; Gedda, G; Rathnakar, B; Satyanarayana, M; Yamajala, B; Ahsan, MJ; Jadav, SS; Balaraju, T A review on HCV inhibitors: Significance of non-structural polyproteins. Eur J Med Chem 164:576-601 (2019) [PubMed]  Article 
Target
Name:
RNA-directed RNA polymerase
Synonyms:
Hepatitis C virus NS5B RNA-dependent RNA polymerase | NS5B protein
Type:
Protein
Mol. Mass.:
25173.95
Organism:
Hepatitis C virus
Description:
Q8JXU8
Residue:
229
Sequence:
RTEEAIYQCCDLDPQARVAIRSLTERLYVGGPLTNSRGENCGYRRRASGVLTTSCGNTLTCYIKAQAACRAAGRQDCTMLVCGDDLVVICESAGVQEDAASLRAFTEAMTRYSAPPGDPPQPEYDLELITSCSSNVSVAHDGAGKRVYYLTRDPTTPLARAAWETARHTPVNSWLGNIIMFAPTLWVRMIMLTHFFSVLIARDQLEQALDCEIYGACYSIEPLLPPIIQ
  
Inhibitor
Name:
BDBM50537570
Synonyms:
CHEMBL474496
Type:
Small organic molecule
Emp. Form.:
C18H11Cl2NO5
Mol. Mass.:
392.19
SMILES:
OC(=O)C(\O)=C\C(=O)c1cccc(OCc2cc(Cl)cc(Cl)c2C#N)c1
Structure:
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