Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50048451
Substrate
n/a
Meas. Tech.
ChEMBL_29477 (CHEMBL640470)
Ki
1060±n/a nM
Citation
 van Rhee, AM; Siddiqi, SM; Melman, N; Shi, D; Padgett, WL; Daly, JW; Jacobson, KA Tetrahydrobenzothiophenone derivatives as a novel class of adenosine receptor antagonists. J Med Chem 39:398-406 (1996) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50048451
Synonyms:
3-Allylsulfanyl-4-oxo-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carboxylic acid ethyl ester | CHEMBL130787
Type:
Small organic molecule
Emp. Form.:
C14H16O3S2
Mol. Mass.:
296.405
SMILES:
CCOC(=O)c1sc(SCC=C)c2c1CCCC2=O
Structure:
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