Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50048457
Substrate
n/a
Meas. Tech.
ChEMBL_32006 (CHEMBL646603)
Ki
35800±n/a nM
Citation
 van Rhee, AM; Siddiqi, SM; Melman, N; Shi, D; Padgett, WL; Daly, JW; Jacobson, KA Tetrahydrobenzothiophenone derivatives as a novel class of adenosine receptor antagonists. J Med Chem 39:398-406 (1996) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50048457
Synonyms:
4-Hydroxy-3-methylsulfanyl-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carboxylic acid ethyl ester | CHEMBL337243
Type:
Small organic molecule
Emp. Form.:
C12H16O3S2
Mol. Mass.:
272.384
SMILES:
CCOC(=O)c1sc(SC)c2C(O)CCCc12
Structure:
Search PDB for entries with ligand similarity: