Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50499690
Substrate
n/a
Meas. Tech.
ChEMBL_1543178 (CHEMBL3744902)
Ki
>200000±n/a nM
Citation
 Moas-Héloire, V; Renault, N; Batalha, V; Arias, AR; Marchivie, M; Yous, S; Deguine, N; Buée, L; Chavatte, P; Blum, D; Lopes, L; Melnyk, P; Agouridas, L Design and synthesis of fused tetrahydroisoquinoline-iminoimidazolines. Eur J Med Chem 106:15-25 (2015) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50499690
Synonyms:
CHEMBL3740152
Type:
Small organic molecule
Emp. Form.:
C17H20ClN3O
Mol. Mass.:
317.813
SMILES:
Cl.Oc1ccc(C[C@H]2CN(Cc3ccccc3)C(=N)N2)cc1 |r|
Structure:
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