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Target
Adenosine receptor A1
Ligand
BDBM50051339
Substrate
n/a
Meas. Tech.
ChEMBL_29152 (CHEMBL639432)
Ki
7320.0±n/a nM
Citation
 Karton, Y; Jiang, JL; Ji, XD; Melman, N; Olah, ME; Stiles, GL; Jacobson, KA Synthesis and biological activities of flavonoid derivatives as A3 adenosine receptor antagonists. J Med Chem 39:2293-301 (1996) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50051339
Synonyms:
3-Hydroxy-2-(2,4,6-trimethoxy-phenyl)-chromen-4-one | CHEMBL76933
Type:
Small organic molecule
Emp. Form.:
C18H16O6
Mol. Mass.:
328.316
SMILES:
COc1cc(OC)c(c(OC)c1)-c1oc2ccccc2c(=O)c1O |(16.48,-10.59,;16.35,-9.06,;14.97,-8.39,;13.7,-9.27,;12.32,-8.6,;11.06,-9.48,;11.17,-11,;12.21,-7.08,;13.47,-6.2,;13.34,-4.68,;14.84,-4.26,;14.85,-6.85,;10.82,-6.41,;9.54,-7.29,;8.16,-6.63,;6.92,-7.51,;5.51,-6.85,;5.38,-5.32,;6.66,-4.44,;8.04,-5.09,;9.3,-4.22,;9.18,-2.7,;10.69,-4.87,;11.96,-4.01,)|
Structure:
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