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Target
Structural capsid protein
Ligand
BDBM50501098
Substrate
n/a
Meas. Tech.
ChEMBL_1587274 (CHEMBL3826198)
IC50
3000±n/a nM
Citation
 Ko?í?ek, M; ?t?pánek, O; Parkan, K; Berenguer Albińana, C; Pávová, M; Weber, J; Kr?usslich, HG; Konvalinka, J; Machara, A Synthesis and evaluation of 2-pyridinylpyrimidines as inhibitors of HIV-1 structural protein assembly. Bioorg Med Chem Lett 26:3487-90 (2016) [PubMed]  Article 
Target
Name:
Structural capsid protein
Synonyms:
Structural capsid protein | gag
Type:
PROTEIN
Mol. Mass.:
12762.23
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_106648
Residue:
115
Sequence:
ELERFAVNPALLETSEGCRQILGQLQPSLQTGSEELKSLFNTVATLYCVHQRIEVKDTKEALDKIEEEQNKSKKKAQQAQQAAAATGSSQVSQNYPIVQNLQGQMVHQPISPRTL
  
Inhibitor
Name:
BDBM50501098
Synonyms:
CHEMBL3823570
Type:
Small organic molecule
Emp. Form.:
C19H17F2N5O
Mol. Mass.:
369.368
SMILES:
Cc1cc(Nc2ccc(C(=O)NCCF)c(F)c2)nc(n1)-c1cccnc1
Structure:
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