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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50053912
Substrate
n/a
Meas. Tech.
ChEMBL_157546 (CHEMBL764930)
Ki
0.075±n/a nM
Citation
 Romines, KR; Morris, JK; Howe, WJ; Tomich, PK; Horng, MM; Chong, KT; Hinshaw, RR; Anderson, DJ; Strohbach, JW; Turner, SR; Mizsak, SA Cycloalkylpyranones and cycloalkyldihydropyrones as HIV protease inhibitors: exploring the impact of ring size on structure-activity relationships. J Med Chem 39:4125-30 (1996) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50053912
Synonyms:
5-Cyano-pyridine-2-sulfonic acid {3-[1-(4-hydroxy-2-oxo-2,5,6,7-tetrahydro-cyclopenta[b]pyran-3-yl)-propyl]-phenyl}-amide | CHEMBL415722
Type:
Small organic molecule
Emp. Form.:
C23H21N3O5S
Mol. Mass.:
451.495
SMILES:
CCC(c1cccc(NS(=O)(=O)c2ccc(cn2)C#N)c1)c1c(O)c2CCCc2oc1=O
Structure:
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