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Target
Integrase
Ligand
BDBM50056894
Substrate
n/a
Meas. Tech.
ChEMBL_90707 (CHEMBL702106)
IC50
>200000±n/a nM
Citation
 Zhao, H; Neamati, N; Sunder, S; Hong, H; Wang, S; Milne, GW; Pommier, Y; Burke, TR Hydrazide-containing inhibitors of HIV-1 integrase. J Med Chem 40:937-41 (1997) [PubMed]  Article 
Target
Name:
Integrase
Synonyms:
Human immunodeficiency virus type 1 integrase
Type:
PROTEIN
Mol. Mass.:
32231.48
Organism:
Human immunodeficiency virus type 1
Description:
ChEMBL_90865
Residue:
288
Sequence:
FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
  
Inhibitor
Name:
BDBM50056894
Synonyms:
2-hydroxy-N-{3-[(2-hydroxybenzoyl)amino]propyl}benzamide | CHEMBL426397 | N,N'-(Propane-1,3-diyl)bis(2-hydroxybenzamide)
Type:
Small organic molecule
Emp. Form.:
C17H18N2O4
Mol. Mass.:
314.3358
SMILES:
Oc1ccccc1C(=O)NCCCNC(=O)c1ccccc1O
Structure:
Search PDB for entries with ligand similarity: