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Target
Integrase
Ligand
BDBM50057341
Substrate
n/a
Meas. Tech.
ChEMBL_90715 (CHEMBL702114)
IC50
230±n/a nM
Citation
 Zhao, H; Neamati, N; Mazumder, A; Sunder, S; Pommier, Y; Burke, TR Arylamide inhibitors of HIV-1 integrase. J Med Chem 40:1186-94 (1997) [PubMed]  Article 
Target
Name:
Integrase
Synonyms:
Human immunodeficiency virus type 1 integrase
Type:
PROTEIN
Mol. Mass.:
32231.48
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_90865
Residue:
288
Sequence:
FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
  
Inhibitor
Name:
BDBM50057341
Synonyms:
2N-[3-(5,6-Dihydroxy-2-naphthyl carboxamido)propyl]-5,6-dihydroxy-2-naphthamide | CHEMBL18635
Type:
Small organic molecule
Emp. Form.:
C25H22N2O6
Mol. Mass.:
446.452
SMILES:
Oc1ccc2cc(ccc2c1O)C(=O)NCCCNC(=O)c1ccc2c(O)c(O)ccc2c1
Structure:
Search PDB for entries with ligand similarity: