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Target
D(3) dopamine receptor
Ligand
BDBM50515233
Substrate
n/a
Meas. Tech.
ChEMBL_1860516 (CHEMBL4361372)
Ki
1.9±n/a nM
Citation
 Battiti, FO; Cemaj, SL; Guerrero, AM; Shaik, AB; Lam, J; Rais, R; Slusher, BS; Deschamps, JR; Imler, GH; Newman, AH; Bonifazi, A The Significance of Chirality in Drug Design and Synthesis of Bitopic Ligands as D J Med Chem 62:6287-6314 (2019) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50515233
Synonyms:
CHEMBL4551160
Type:
Small organic molecule
Emp. Form.:
C25H31N5O2
Mol. Mass.:
433.5459
SMILES:
C[C@H]1CO[C@H](CN1C[C@H]1C[C@@H]1CCNC(=O)c1cc2ccccc2[nH]1)c1ccc(N)nc1 |r|
Structure:
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