Reaction Details Report a problem with these data
Target
Reverse transcriptase
Ligand
BDBM71542
Substrate
n/a
Meas. Tech.
ChEMBL_1872148 (CHEMBL4373315)
IC50
100000±n/a nM
Citation
 Jain, N; Friedman, SH Multiple weak intercalation as a strategy for the inhibition of polymerases. Bioorg Med Chem Lett 29:424-429 (2019) [PubMed]  Article 
Target
Name:
Reverse transcriptase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
29598.37
Organism:
Human immunodeficiency virus 1
Description:
Q9WKE8
Residue:
254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVN
  
Inhibitor
Name:
BDBM71542
Synonyms:
(4-amino-1-methyl-butyl)-(6-methoxy-8-quinolyl)amine;phosphoric acid | 4-N-(6-methoxyquinolin-8-yl)pentane-1,4-diamine;phosphoric acid | MLS001334045 | N4-(6-methoxy-8-quinolinyl)pentane-1,4-diamine;phosphoric acid | N4-(6-methoxyquinolin-8-yl)pentane-1,4-diamine;phosphoric acid | Primaquine bisphosphate | SMR000875314 | cid_359247
Type:
Small organic molecule
Emp. Form.:
C15H21N3O
Mol. Mass.:
259.3467
SMILES:
COc1cc(NC(C)CCCN)c2ncccc2c1
Structure:
Search PDB for entries with ligand similarity: