Reaction Details Report a problem with these data
Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50073336
Substrate
n/a
Meas. Tech.
ChEMBL_157537 (CHEMBL764922)
Ki
>10000±n/a nM
Citation
 Baker, CT; Salituro, FG; Court, JJ; Deininger, DD; Kim, EE; Li, B; Novak, PM; Rao, BG; Pazhanisamy, S; Schairer, WC; Tung, RD Design, synthesis, and conformational analysis of a novel series of HIV protease inhibitors. Bioorg Med Chem Lett 8:3631-6 (1999) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50073336
Synonyms:
CHEMBL121376 | N-Cyclopentylmethyl-N-[(S)-2-hydroxy-3-(3-isopropyl-1-phenethyl-ureido)-propyl]-4-methoxy-benzenesulfonamide
Type:
Small organic molecule
Emp. Form.:
C28H41N3O5S
Mol. Mass.:
531.707
SMILES:
COc1ccc(cc1)S(=O)(=O)N(C[C@@H](O)CN(CCc1ccccc1)C(=O)NC(C)C)CC1CCCC1
Structure:
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