Reaction Details Report a problem with these data
Target
Melatonin receptor type 1B
Ligand
BDBM76093
Substrate
n/a
Meas. Tech.
ChEMBL_1888565 (CHEMBL4390242)
EC50
244000±n/a nM
Citation
 Chen, SY; Geng, CA; Ma, YB; Huang, XY; Yang, XT; Su, LH; He, XF; Li, TZ; Deng, ZT; Gao, Z; Zhang, XM; Chen, JJ Polybenzyls from Gastrodia elata, their agonistic effects on melatonin receptors and structure-activity relationships. Bioorg Med Chem 27:3299-3306 (2019) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1B
Synonyms:
MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:
Enzyme
Mol. Mass.:
40203.54
Organism:
Homo sapiens (Human)
Description:
P49286
Residue:
362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
  
Inhibitor
Name:
BDBM76093
Synonyms:
4-(4-hydroxybenzyl)phenol | 4-[(4-hydroxyphenyl)methyl]phenol | KSC-19-052 | KUC106448N | cid_12111
Type:
Small organic molecule
Emp. Form.:
C13H12O2
Mol. Mass.:
200.2332
SMILES:
Oc1ccc(Cc2ccc(O)cc2)cc1
Structure:
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