Reaction Details Report a problem with these data
Target
Cytochrome c oxidase subunit 2
Ligand
BDBM50524076
Substrate
n/a
Meas. Tech.
ChEMBL_1891730 (CHEMBL4393557)
IC50
66100±n/a nM
Citation
 Singh, R; Mandrah, K; Asati, A; Patel, DK; Goel, B; Vishwakarma, RA; Roy, SK; Jain, SK Transformation of Santonin to a Naproxen Analogue with Anti-Inflammatory Activity. J Nat Prod 82:1710-1713 (2019) [PubMed]  Article 
Target
Name:
Cytochrome c oxidase subunit 2
Synonyms:
COII | COX2 | COX2_HUMAN | COXII | MT-CO2 | MTCO2
Type:
PROTEIN
Mol. Mass.:
25555.66
Organism:
Homo sapiens (Human)
Description:
ChEMBL_530099
Residue:
227
Sequence:
MAHAAQVGLQDATSPIMEELITFHDHALMIIFLICFLVLYALFLTLTTKLTNTNISDAQEMETVWTILPAIILVLIALPSLRILYMTDEVNDPSLTIKSIGHQWYWTYEYTDYGGLIFNSYMLPPLFLEPGDLRLLDVDNRVVLPIEAPIRMMITSQDVLHSWAVPTLGLKTDAIPGRLNQTTFTATRPGVYYGQCSEICGANHSFMPIVLELIPLKIFEMGPVFTL
  
Inhibitor
Name:
BDBM50524076
Synonyms:
CHEMBL4483707
Type:
Small organic molecule
Emp. Form.:
C16H18O3
Mol. Mass.:
258.3123
SMILES:
COC(=O)[C@@H](C)c1ccc2c(C)cc(O)c(C)c2c1 |r|
Structure:
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