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Target
Bcl-2-like protein 1
Ligand
BDBM50266957
Substrate
n/a
Meas. Tech.
ChEMBL_1896437 (CHEMBL4398472)
Ki
1500±n/a nM
Citation
 Yang, S; Mao, Y; Zhang, H; Xu, Y; An, J; Huang, Z The chemical biology of apoptosis: Revisited after 17 years. Eur J Med Chem 177:63-75 (2019) [PubMed]  Article 
Target
Name:
Bcl-2-like protein 1
Synonyms:
Anti-apoptotic Bcl-2 protein | Apoptosis Regulator Bcl-xL | Apoptosis regulator Bcl-X | B2CL1_HUMAN | BCL2-like 1 isoform 1 | BCL2L | BCL2L1 | BCLX | Bcl-2-like protein 1 (Bcl-XL) | Bcl-X | Bcl-xL/Bcl-2-binding component 3 | Bcl2-L-1 | Bcl2-antagonist of cell death (BAD)
Type:
Mitochondrion membrane; Single-pass membrane protein
Mol. Mass.:
26039.60
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
233
Sequence:
MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK
  
Inhibitor
Name:
BDBM50266957
Synonyms:
CHEMBL2070024
Type:
Small organic molecule
Emp. Form.:
C38H48N2O5
Mol. Mass.:
612.7981
SMILES:
[NH4+].[NH4+].CC(C)Cc1cc(ccc1OCC([O-])=O)-c1ccc(cc1Cc1ccccc1)-c1ccc(CCC([O-])=O)cc1CC(C)C
Structure:
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