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Target
D(3) dopamine receptor
Ligand
BDBM50530575
Substrate
n/a
Meas. Tech.
ChEMBL_1913342 (CHEMBL4415925)
Ki
4.3±n/a nM
Citation
 Shaik, AB; Kumar, V; Bonifazi, A; Guerrero, AM; Cemaj, SL; Gadiano, A; Lam, J; Xi, ZX; Rais, R; Slusher, BS; Newman, AH Investigation of Novel Primary and Secondary Pharmacophores and 3-Substitution in the Linking Chain of a Series of Highly Selective and Bitopic Dopamine D J Med Chem 62:9061-9077 (2019) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50530575
Synonyms:
CHEMBL4463620
Type:
Small organic molecule
Emp. Form.:
C26H32N4O4
Mol. Mass.:
464.5567
SMILES:
CCc1cc2OCOc2cc1N1CCN(CC(O)CCNC(=O)c2cc3ccccc3[nH]2)CC1
Structure:
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