Reaction Details Report a problem with these data
Target
Acyl-protein thioesterase 1
Ligand
BDBM50543969
Substrate
n/a
Meas. Tech.
ChEMBL_1990948 (CHEMBL4624683)
Ki
23±n/a nM
Citation
 Zhang, B; Liu, F; Yang, MF; Xu, J; Wang, Z; Zhang, J; Wang, R; Yang, X A cell-based fluorescent assay for FAP inhibitor discovery. Bioorg Med Chem Lett 30:0 (2020) [PubMed]  Article 
Target
Name:
Acyl-protein thioesterase 1
Synonyms:
Acyl-protein thioesterase 1/2 | Apt1 | LYPA1_RAT | Lypla1 | Lysosomal phospholipase A1
Type:
PROTEIN
Mol. Mass.:
24708.49
Organism:
Rattus norvegicus
Description:
ChEMBL_12731
Residue:
230
Sequence:
MCGNNMSAPMPAVVPAARKATAAVIFLHGLGDTGHGWAEAFAGIKSSHIKYICPHAPVMPVTLNMSMMMPSWFDIIGLSPDSQEDESGIKQAAETVKALIDQEVKNGIPSNRIILGGFSQGGALSLYTALTTQQKLAGVTALSCWLPLRASFSQGPINSANRDISVLQCHGDCDPLVPLMFGSLTVERLKGLVNPANVTFKVYEGMMHSSCQQEMMDVKYFIDKLLPPID
  
Inhibitor
Name:
BDBM50543969
Synonyms:
CHEMBL4640030
Type:
Small organic molecule
Emp. Form.:
C8H15BN2O4
Mol. Mass.:
214.027
SMILES:
CC(=O)NCC(=O)N1CCC[C@@H]1B(O)O |r|
Structure:
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