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Target
Galectin-8
Ligand
BDBM50370453
Substrate
n/a
Meas. Tech.
ChEMBL_2016288 (CHEMBL4669866)
Kd
37920±n/a nM
Citation
 Patel, B; Kishor, C; Houston, TA; Shatz-Azoulay, H; Zick, Y; Vinik, Y; Blanchard, H Rational Design and Synthesis of Methyl-?-d-galactomalonyl Phenyl Esters as Potent Galectin-8 J Med Chem 63:11573-11584 (2020) [PubMed] 
Target
Name:
Galectin-8
Synonyms:
Gal-8 | LEG8_HUMAN | LGALS8 | PCTA-1 | Po66 carbohydrate-binding protein | Po66-CBP | Prostate carcinoma tumor antigen 1
Type:
PROTEIN
Mol. Mass.:
35814.23
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1454625
Residue:
317
Sequence:
MMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRADVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGTPQLRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFVRNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSIDTLEINGDIHLLEVRSW
  
Inhibitor
Name:
BDBM50370453
Synonyms:
LACTOSE | Lactose, anhydrous
Type:
Small organic molecule
Emp. Form.:
C12H22O11
Mol. Mass.:
342.2965
SMILES:
OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O |r|
Structure:
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