Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50549966
Substrate
n/a
Meas. Tech.
ChEMBL_2026016 (CHEMBL4679829)
Ki
1000±n/a nM
Citation
 Kargbo, RB Sigma-1 and Sigma-2 Receptor Modulators as Potential Therapeutics for Alzheimer's Disease. ACS Med Chem Lett 12:178-179 (2021) [PubMed]  Article 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20857.20
Organism:
Homo sapiens (Human)
Description:
Q5BJF2
Residue:
176
Sequence:
MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
  
Inhibitor
Name:
BDBM50549966
Synonyms:
CHEMBL4745019
Type:
Small organic molecule
Emp. Form.:
C18H21FN4O
Mol. Mass.:
328.3839
SMILES:
CN1CCn2nc3CCC(Cc3c2C1=O)NCc1ccc(F)cc1
Structure:
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