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Target
Translocator protein
Ligand
BDBM50553134
Substrate
n/a
Meas. Tech.
ChEMBL_2045209 (CHEMBL4699908)
Ki
3282±n/a nM
Citation
 Vo, SV; Banister, SD; Freelander, I; Werry, EL; Reekie, TA; Ittner, LM; Kassiou, M Reversing binding sensitivity to A147T translocator protein. RSC Med Chem 11:511-517 (2020) [PubMed]  Article 
Target
Name:
Translocator protein
Synonyms:
BZRP | MBR | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor | TSPO | TSPO_HUMAN
Type:
Enzyme
Mol. Mass.:
18834.74
Organism:
Homo sapiens (Human)
Description:
P30536
Residue:
169
Sequence:
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
  
Inhibitor
Name:
BDBM50553134
Synonyms:
CHEMBL4758870
Type:
Small organic molecule
Emp. Form.:
C20H19N3O2
Mol. Mass.:
333.3838
SMILES:
COc1ccc(Cn2c(nc3ccccc23)C(=O)N(C)CC#C)cc1
Structure:
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