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Target
C-X-C chemokine receptor type 2
Ligand
BDBM50102222
Substrate
n/a
Meas. Tech.
ChEBML_44675
IC50
10±n/a nM
Citation
 Cutshall, NS; Kucera, KA; Ursino, R; Latham, J; Ihle, NC Nicotinanilides as inhibitors of neutrophil chemotaxis. Bioorg Med Chem Lett 12:1517-20 (2002) [PubMed]  Article 
Target
Name:
C-X-C chemokine receptor type 2
Synonyms:
C-X-C chemokine receptor type 2 (CXCR-2) | C-X-C chemokine receptor type 2 (CXCR2) | CD_antigen=CD182 | CDw128b | CXCR-2 | CXCR2 | CXCR2_HUMAN | Chemokine receptor type 2 (CXCR2) | GRO/MGSA receptor | High affinity interleukin-8 receptor B | IL-8 receptor type 2 | IL-8R B | IL8RB | Interleukin-8 receptor B
Type:
Protein
Mol. Mass.:
40767.88
Organism:
Homo sapiens (Human)
Description:
P25025
Residue:
360
Sequence:
MEDFNMESDSFEDFWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLSIWGLSLLLALPVLLFRRTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSLPKDSRPSFVGSSSGHTSTTL
  
Inhibitor
Name:
BDBM50102222
Synonyms:
1-(2-Bromo-phenyl)-3-(7-cyano-3H-benzotriazol-4-yl)-urea | CHEMBL38182
Type:
Small organic molecule
Emp. Form.:
C14H9BrN6O
Mol. Mass.:
357.165
SMILES:
Brc1ccccc1NC(=O)Nc1ccc(C#N)c2nn[nH]c12
Structure:
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