Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50559053
Substrate
n/a
Meas. Tech.
ChEMBL_2067567 (CHEMBL4722820)
Ki
82±n/a nM
Citation
 Federico, S; Margiotta, E; Moro, S; Kozma, E; Gao, ZG; Jacobson, KA; Spalluto, G Conjugable A Eur J Med Chem 186:0 (2020) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50559053
Synonyms:
CHEMBL4779646
Type:
Small organic molecule
Emp. Form.:
C35H45N9O9
Mol. Mass.:
735.7867
SMILES:
Cn1cc2c(n1)nc(NC(=O)Nc1ccc(CC(=O)OCCCOCCOCCOCCCNC(=O)OC(C)(C)C)cc1)n1nc(nc21)-c1ccco1
Structure:
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