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Target
Platelet-activating factor receptor
Ligand
BDBM50123631
Substrate
n/a
Meas. Tech.
ChEMBL_155145 (CHEMBL760186)
Ki
1620±n/a nM
Citation
 Vogensen, SB; Strømgaard, K; Shindou, H; Jaracz, S; Suehiro, M; Ishii, S; Shimizu, T; Nakanishi, K Preparation of 7-substituted ginkgolide derivatives: potent platelet activating factor (PAF) receptor antagonists. J Med Chem 46:601-8 (2003) [PubMed]  Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50123631
Synonyms:
8-(tert-butyl)-6,12,17-trihydroxy-16-methyl-9-ethylamino-(6R,8R,9R,12R,16S,17R)-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione | CHEMBL433516
Type:
Small organic molecule
Emp. Form.:
C22H29NO10
Mol. Mass.:
467.4664
SMILES:
CCN[C@H]1C2OC(=O)C34OC5OC(=O)[C@H](O)C5(C1C(C)(C)C)C23[C@@H](O)C1OC(=O)[C@@H](C)[C@]41O
Structure:
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