Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50578454
Substrate
n/a
Meas. Tech.
ChEMBL_2132885 (CHEMBL4842495)
Ki
19±n/a nM
Citation
 Mohr, F; Hurrle, T; Burggraaff, L; Langer, L; Bemelmans, MP; Knab, M; Nieger, M; van Westen, GJP; Heitman, LH; Bräse, S Synthesis and SAR evaluation of coumarin derivatives as potent cannabinoid receptor agonists. Eur J Med Chem 220:0 (2021) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50578454
Synonyms:
CHEMBL4854325
Type:
Small organic molecule
Emp. Form.:
C21H28O3
Mol. Mass.:
328.4452
SMILES:
CCCCC1(CCCC1)c1cc(O)c2cc(CCC)c(=O)oc2c1
Structure:
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