Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50149116
Substrate
n/a
Meas. Tech.
ChEBML_31415
IC50
10±n/a nM
Citation
 Okamura, T; Kurogi, Y; Hashimoto, K; Sato, S; Nishikawa, H; Kiryu, K; Nagao, Y Structure-activity relationships of adenosine A3 receptor ligands: new potential therapy for the treatment of glaucoma. Bioorg Med Chem Lett 14:3775-9 (2004) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50149116
Synonyms:
4-(5-Butyl-[1,2,4]triazolo[1,5-c]quinazolin-2-yl)-phenol | CHEMBL338057
Type:
Small organic molecule
Emp. Form.:
C19H18N4O
Mol. Mass.:
318.3724
SMILES:
CCCCc1nc2ccccc2c2nc(nn12)-c1ccc(O)cc1
Structure:
Search PDB for entries with ligand similarity: