Reaction Details Report a problem with these data
Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM50468262
Substrate
n/a
Meas. Tech.
ChEMBL_2264083
IC50
21000±n/a nM
Citation
 Gendaszewska-Darmach, E; Garstka, MA; B?a?ewska, KM Targeting Small GTPases and Their Prenylation in Diabetes Mellitus. J Med Chem 64:9677-9710 (2021) [PubMed] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1 | RAC1_HUMAN | Ras-related C3 botulinum toxin substrate 1 | Ras-related C3 botulinum toxin substrate 1/T-lymphoma invasion and metastasis-inducing protein 1 | TC25
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1337921
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM50468262
Synonyms:
CHEMBL4277903
Type:
Small organic molecule
Emp. Form.:
C16H16F3N3
Mol. Mass.:
307.3135
SMILES:
Cc1cc(C)cc(NC(=N)Nc2ccccc2C(F)(F)F)c1
Structure:
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