Reaction Details Report a problem with these data
Target
Peroxisome proliferator-activated receptor delta
Ligand
BDBM50594422
Substrate
n/a
Meas. Tech.
ChEMBL_2212710 (CHEMBL5125659)
Ki
1000±n/a nM
Citation
 Nguyen, M; An, S; Nguyen, Y; Hyun, YE; Choi, H; Pham, L; Kim, JA; Noh, M; Kim, G; Jeong, LS Design, Synthesis, and Biological Activity of l-1'-Homologated Adenosine Derivatives. ACS Med Chem Lett 13:1131-1136 (2022) [PubMed] 
Target
Name:
Peroxisome proliferator-activated receptor delta
Synonyms:
NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta
Type:
Enzyme
Mol. Mass.:
49910.45
Organism:
Human
Description:
Q03181
Residue:
441
Sequence:
MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDMY
  
Inhibitor
Name:
BDBM50594422
Synonyms:
CHEMBL5208616
Type:
Small organic molecule
Emp. Form.:
C17H17ClIN5O3
Mol. Mass.:
501.706
SMILES:
O[C@H]1CO[C@H](Cn2cnc3c(NCc4cccc(I)c4)nc(Cl)nc23)[C@H]1O |r|
Structure:
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