Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50176412
Substrate
n/a
Meas. Tech.
ChEMBL_333261 (CHEMBL859080)
Ki
>10000±n/a nM
Citation
 Carpino, PA; Griffith, DA; Sakya, S; Dow, RL; Black, SC; Hadcock, JR; Iredale, PA; Scott, DO; Fichtner, MW; Rose, CR; Day, R; Dibrino, J; Butler, M; Debartolo, DB; Dutcher, D; Gautreau, D; Lizano, JS; O'connor, RE; Sands, MA; Kelly-Sullivan, D; Ward, KM New bicyclic cannabinoid receptor-1 (CB1-R) antagonists. Bioorg Med Chem Lett 16:731-6 (2005) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50176412
Synonyms:
6-benzyl-2-(2-chlorophenyl)-3-(4-chlorophenyl)-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one | CHEMBL379667
Type:
Small organic molecule
Emp. Form.:
C24H16Cl2N4O
Mol. Mass.:
447.316
SMILES:
Clc1ccc(cc1)-c1n(nc2c1ncn(Cc1ccccc1)c2=O)-c1ccccc1Cl
Structure:
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