Reaction Details Report a problem with these data
Target
Stefin-3
Ligand
BDBM50257137
Substrate
n/a
Meas. Tech.
ChEMBL_2267459
IC50
15±n/a nM
Citation
 Liu, Z; Wang, P; Wold, EA; Song, Q; Zhao, C; Wang, C; Zhou, J Small-Molecule Inhibitors Targeting the Canonical WNT Signaling Pathway for the Treatment of Cancer. J Med Chem 64:4257-4288 (2021) [PubMed] 
Target
Name:
Stefin-3
Synonyms:
Stefin-3 | Stf-3 | Stf3 | Stfa3
Type:
PROTEIN
Mol. Mass.:
11639.70
Organism:
Mus musculus
Description:
ChEMBL_120950
Residue:
103
Sequence:
MSQENLKIKGGLSEARPATPEIQMIADKVRPLLEEQTNEKYEKFEAVEYKSQVVAGQNLFIKIDVGNGCFLHMKVFRGLSGEDDLKLKGYQTNKTKTDELTSM
  
Inhibitor
Name:
BDBM50257137
Synonyms:
CHEMBL4094309
Type:
Small organic molecule
Emp. Form.:
C19H18N4O3S
Mol. Mass.:
382.436
SMILES:
CN1C(=O)C2=C(N(CC(=O)Nc3ccc(cc3)-c3nccs3)CCC2)C1=O |t:4|
Structure:
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