Reaction Details Report a problem with these data
Target
Muscleblind-like protein 1
Ligand
BDBM50408491
Substrate
n/a
Meas. Tech.
ChEMBL_2267824
Kd
>200000±n/a nM
Citation
 Zamani, F; Suzuki, T Synthetic RNA Modulators in Drug Discovery. J Med Chem 64:7110-7155 (2021) [PubMed] 
Target
Name:
Muscleblind-like protein 1
Synonyms:
EXP | KIAA0428 | MBNL | MBNL1 | Muscleblind-like protein 1 | Triplet-expansion RNA-binding protein
Type:
PROTEIN
Mol. Mass.:
41833.94
Organism:
Homo sapiens
Description:
ChEMBL_103750
Residue:
388
Sequence:
MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGAPLQPVPMFSVAPSLATNASAAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMTQSAVKSLKRPLEATFDLGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPVPMVHGATPATVSAATTSATSVPFAATATANQIPIISAEHLTSHKYVTQM
  
Inhibitor
Name:
BDBM50408491
Synonyms:
CHEMBL4437685
Type:
Small organic molecule
Emp. Form.:
C22H34N16
Mol. Mass.:
522.6126
SMILES:
Nc1nc(N)nc(NCCCCNC(=N)c2ccc(cc2)C(=N)NCCCCNc2nc(N)nc(N)n2)n1
Structure:
Search PDB for entries with ligand similarity: