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Target
Translocator protein
Ligand
BDBM50409613
Substrate
n/a
Meas. Tech.
ChEMBL_2268395
Ki
0.300000±n/a nM
Citation
 Giordani, A; Menziani, MC; Moresco, RM; Matarrese, M; Paolino, M; Saletti, M; Giuliani, G; Anzini, M; Cappelli, A Exploring Translocator Protein (TSPO) Medicinal Chemistry: An Approach for Targeting Radionuclides and Boron Atoms to Mitochondria. J Med Chem 64:9649-9676 (2021) [PubMed] 
Target
Name:
Translocator protein
Synonyms:
BZRP | MBR | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor | TSPO | TSPO_HUMAN
Type:
Enzyme
Mol. Mass.:
18834.74
Organism:
Human
Description:
P30536
Residue:
169
Sequence:
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
  
Inhibitor
Name:
BDBM50409613
Synonyms:
CHEMBL5275028
Type:
Small organic molecule
Emp. Form.:
C24H23FO4
Mol. Mass.:
393.438
SMILES:
COc1ccc(OC)c(CC(C(=O)C[18F])c2ccccc2Oc2ccccc2)c1
Structure:
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