Reaction Details Report a problem with these data
Target
Arginase-1
Ligand
BDBM50354832
Substrate
n/a
Meas. Tech.
ChEMBL_2272757
Ki
60000±n/a nM
Citation
 Xiao, YC; Yu, JL; Dai, QQ; Li, G; Li, GB Targeting Metalloenzymes by Boron-Containing Metal-Binding Pharmacophores. J Med Chem 64:17706-17727 (2021) [PubMed] 
Target
Name:
Arginase-1
Synonyms:
ARGI1_RAT | Arg1 | Liver-type arginase | Type I arginase
Type:
PROTEIN
Mol. Mass.:
34976.26
Organism:
Rattus norvegicus
Description:
ChEMBL_108287
Residue:
323
Sequence:
MSSKPKPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGTKREGNHKPETDYLKPPK
  
Inhibitor
Name:
BDBM50354832
Synonyms:
CHEMBL1834160
Type:
Small organic molecule
Emp. Form.:
C7H13NO3
Mol. Mass.:
159.183
SMILES:
N[C@@H](CCCCC=O)C(O)=O |r|
Structure:
Search PDB for entries with ligand similarity: