Reaction Details Report a problem with these data
Target
Lysophosphatidic acid receptor 1
Ligand
BDBM50610650
Substrate
n/a
Meas. Tech.
ChEMBL_2281722
EC50
<50±n/a nM
Citation
 Meduri, B; Pujar, GV; Durai Ananda Kumar, T; Akshatha, HS; Sethu, AK; Singh, M; Kanagarla, A; Mathew, B Lysophosphatidic acid (LPA) receptor modulators: Structural features and recent development. Eur J Med Chem 222:0 (2021) [PubMed] 
Target
Name:
Lysophosphatidic acid receptor 1
Synonyms:
EDG2 | LPA receptor 1 | LPA-1 | LPA1 | LPAR1 | LPAR1_HUMAN | Lysophosphatidic acid receptor 1 (LPA1) | Lysophosphatidic acid receptor Edg-2
Type:
Enzyme
Mol. Mass.:
41120.55
Organism:
Homo sapiens (Human)
Description:
Q92633
Residue:
364
Sequence:
MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSNDHSVV
  
Inhibitor
Name:
BDBM50610650
Synonyms:
CHEMBL5285905
Type:
Small organic molecule
Emp. Form.:
C30H27ClN2O5
Mol. Mass.:
530.999
SMILES:
CC(OC(=O)Nc1c(C)noc1-c1ccc(cc1)-c1ccc(CC(O)=O)c2CCCc12)c1ccccc1Cl
Structure:
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