Reaction Details
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Report a problem with these dataTarget
Lysophosphatidic acid receptor 1
Ligand
BDBM50610651
Substrate
n/a
Meas. Tech.
ChEMBL_2281722
EC50
<50±n/a nM
Citation
Meduri, B; Pujar, GV; Durai Ananda Kumar, T; Akshatha, HS; Sethu, AK; Singh, M; Kanagarla, A; Mathew, B Lysophosphatidic acid (LPA) receptor modulators: Structural features and recent development. Eur J Med Chem 222:0 (2021) [PubMed] More Info.:
Target
Name:
Lysophosphatidic acid receptor 1
Synonyms:
EDG2 | LPA receptor 1 | LPA-1 | LPA1 | LPAR1 | LPAR1_HUMAN | Lysophosphatidic acid receptor 1 (LPA1) | Lysophosphatidic acid receptor Edg-2
Type:
Enzyme
Mol. Mass.:
41120.55
Organism:
Homo sapiens (Human)
Description:
Q92633
Residue:
364
Sequence:
MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSNDHSVV
Inhibitor
Name:
BDBM50610651
Synonyms:
CHEMBL5277897
Type:
Small organic molecule
Emp. Form.:
C32H25N2NaO5
Mol. Mass.:
540.5411
SMILES:
[Na;v0+].[#6]-[#6](-[#8]-[#6](=O)-[#7]-c1c(oc2cnccc12)-c1ccc(cc1)-c1ccc(cc1)C1([#6]-[#6]1)[#6](-[#8-])=O)-c1ccccc1
Structure:
