Reaction Details Report a problem with these data
Target
Corticoliberin
Ligand
BDBM50610720
Substrate
n/a
Meas. Tech.
ChEMBL_2281773
Ki
0.700000±n/a nM
Citation
 Alizadeh, SR; Ebrahimzadeh, MA Pyrazolotriazines: Biological activities, synthetic strategies and recent developments. Eur J Med Chem 223:0 (2021) [PubMed] 
Target
Name:
Corticoliberin
Synonyms:
CRF | CRH | Corticoliberin | Corticotropin-releasing factor | Corticotropin-releasing hormone
Type:
PROTEIN
Mol. Mass.:
21428.57
Organism:
Homo sapiens
Description:
ChEMBL_120921
Residue:
196
Sequence:
MRLPLLVSAGVLLVALLPCPPCRALLSRGPVPGARQAPQHPQPLDFFQPPPQSEQPQQPQARPVLLRMGEEYFLRLGNLNKSPAAPLSPASSLLAGGSGSRPSPEQATANFFRVLLQQLLLPRRSLDSPAALAERGARNALGGHQEAPERERRSEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEIIGK
  
Inhibitor
Name:
BDBM50610720
Synonyms:
CHEMBL5286255
Type:
Small organic molecule
Emp. Form.:
C23H31ClN4O2
Mol. Mass.:
430.971
SMILES:
CCCC(CCC)c1c(CC)nn2c(nc(C)nc12)-c1cc(OC)c(OC)cc1Cl
Structure:
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