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Target
L-amino-acid oxidase
Ligand
BDBM50611541
Substrate
n/a
Meas. Tech.
ChEMBL_2283920
EC50
5.0±n/a nM
Citation
 Abdel-Magid, AF Inhibitors of Interleukin 4 Induced Protein 1 (IL4I1) as Potential Treatment for Cancer. ACS Med Chem Lett 14:127-128 (2023) [PubMed] 
Target
Name:
L-amino-acid oxidase
Synonyms:
1.4.3.2 | 1.4.3.25 | IL4-induced protein 1 | IL4I1 | Interleukin-4-induced protein 1 | L-amino-acid oxidase | LAAO | LAO | Protein Fig-1 | Synonyms=FIG1 | hFIG1 | hIL4I1
Type:
PROTEIN
Mol. Mass.:
62897.87
Organism:
Human
Description:
ChEMBL_120957
Residue:
567
Sequence:
MAPLALHLLVLVPILLSLVASQDWKAERSQDPFEKCMQDPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGGRIFTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGLNLTKFTQYDKNTWTEVHEVKLRNYVVEKVPEKLGYALRPQEKGHSPEDIYQMALNQALKDLKALGCRKAMKKFERHTLLEYLLGEGNLSRPAVQLLGDVMSEDGFFYLSFAEALRAHSCLSDRLQYSRIVGGWDLLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQIETSPPARNLKVLKADVVLLTASGPAVKRITFSPPLPRHMQEALRRLHYVPATKVFLSFRRPFWREEHIEGGHSNTDRPSRMIFYPPPREGALLLASYTWSDAAAAFAGLSREEALRLALDDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQPPALWQTEKDDWTVPYGRIYFAGEHTAYPHGWVETAVKSALRAAIKINSRKGPASDTASPEGHASDMEGQGHVHGVASSPSHDLAKEEGSHPPVQGQLSLQNTTHTRTSH
  
Inhibitor
Name:
BDBM50611541
Synonyms:
CHEMBL5269844
Type:
Small organic molecule
Emp. Form.:
C17H17FN4O2S
Mol. Mass.:
360.406
SMILES:
Fc1cccc(c1)-c1nnc(CN2CCN(C3CCC3)C(=O)C2=O)s1
Structure:
Search PDB for entries with ligand similarity: