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Target
L-amino-acid oxidase
Ligand
BDBM50611546
Substrate
n/a
Meas. Tech.
ChEMBL_2283920
EC50
20±n/a nM
Citation
 Abdel-Magid, AF Inhibitors of Interleukin 4 Induced Protein 1 (IL4I1) as Potential Treatment for Cancer. ACS Med Chem Lett 14:127-128 (2023) [PubMed] 
Target
Name:
L-amino-acid oxidase
Synonyms:
1.4.3.2 | 1.4.3.25 | IL4-induced protein 1 | IL4I1 | Interleukin-4-induced protein 1 | L-amino-acid oxidase | LAAO | LAO | Protein Fig-1 | Synonyms=FIG1 | hFIG1 | hIL4I1
Type:
PROTEIN
Mol. Mass.:
62897.87
Organism:
Human
Description:
ChEMBL_120957
Residue:
567
Sequence:
MAPLALHLLVLVPILLSLVASQDWKAERSQDPFEKCMQDPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGGRIFTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGLNLTKFTQYDKNTWTEVHEVKLRNYVVEKVPEKLGYALRPQEKGHSPEDIYQMALNQALKDLKALGCRKAMKKFERHTLLEYLLGEGNLSRPAVQLLGDVMSEDGFFYLSFAEALRAHSCLSDRLQYSRIVGGWDLLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQIETSPPARNLKVLKADVVLLTASGPAVKRITFSPPLPRHMQEALRRLHYVPATKVFLSFRRPFWREEHIEGGHSNTDRPSRMIFYPPPREGALLLASYTWSDAAAAFAGLSREEALRLALDDVAALHGPVVRQLWDGTGVVKRWAEDQHSQGGFVVQPPALWQTEKDDWTVPYGRIYFAGEHTAYPHGWVETAVKSALRAAIKINSRKGPASDTASPEGHASDMEGQGHVHGVASSPSHDLAKEEGSHPPVQGQLSLQNTTHTRTSH
  
Inhibitor
Name:
BDBM50611546
Synonyms:
CHEMBL5265950
Type:
Small organic molecule
Emp. Form.:
C20H22N4O2
Mol. Mass.:
350.4143
SMILES:
CC(N1CCN(C2CCC2)C(=O)C1=O)c1cnc(cn1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: