Reaction Details Report a problem with these data
Target
Glucagon receptor
Ligand
BDBM50611795
Substrate
n/a
Meas. Tech.
ChEMBL_2284251
IC50
110±n/a nM
Citation
 Kerru, N; Singh-Pillay, A; Awolade, P; Singh, P Current anti-diabetic agents and their molecular targets: A review. Eur J Med Chem 152:436-488 (2018) [PubMed] 
Target
Name:
Glucagon receptor
Synonyms:
GL-R | GLR_RAT | Gcgr
Type:
PROTEIN
Mol. Mass.:
55053.40
Organism:
Rattus norvegicus
Description:
ChEMBL_1450588
Residue:
485
Sequence:
MLLTQLHCPYLLLLLVVLSCLPKAPSAQVMDFLFEKWKLYSDQCHHNLSLLPPPTELVCNRTFDKYSCWPDTPPNTTANISCPWYLPWYHKVQHRLVFKRCGPDGQWVRGPRGQSWRDASQCQMDDDEIEVQKGVAKMYSSYQVMYTVGYSLSLGALLLALVILLGLRKLHCTRNYIHGNLFASFVLKAGSVLVIDWLLKTRYSQKIGDDLSVSVWLSDGAVAGCRVATVIMQYGIIANYCWLLVEGVYLYSLLSITTFSEKSFFSLYLCIGWGSPLLFVIPWVVVKCLFENVQCWTSNDNMGFWWILRIPVLLAILINFFIFVRIIHLLVAKLRAHQMHYADYKFRLARSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSTKLFFDLFFSSFQGLLVAVLYCFLNKEVQAELLRRWRRWQEGKALQEERMASSHGSHMAPAGTCHGDPCEKLQLMSAGSSSGTGCEPSAKTSLASSLPRLADSPT
  
Inhibitor
Name:
BDBM50611795
Synonyms:
CHEMBL5277926
Type:
Small organic molecule
Emp. Form.:
C23H31FO
Mol. Mass.:
342.49
SMILES:
CCCc1c(cc(C(C)C)c([C@@H](C)O)c1-c1ccc(F)cc1)C(C)C |r|
Structure:
Search PDB for entries with ligand similarity: