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Target
Mu-type opioid receptor
Ligand
BDBM50210550
Substrate
n/a
Meas. Tech.
ChEMBL_444088 (CHEMBL893251)
IC50
380±n/a nM
Citation
 Peng, X; Knapp, BI; Bidlack, JM; Neumeyer, JL In-vitro investigation of oxazol and urea analogues of morphinan at opioid receptors. Bioorg Med Chem 15:4106-12 (2007) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50210550
Synonyms:
CHEMBL242968 | MCL-448 | N-cyclopropylmethylmorphinan-3-amino-urea
Type:
Small organic molecule
Emp. Form.:
C21H29N3O
Mol. Mass.:
339.4745
SMILES:
NC(=O)Nc1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CC3)c2c1 |TLB:19:18:7.23.8:10|
Structure:
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